Composition comprising P53-activating peptide
US12370234B2 · kind B2 · utility
0Cited by
3References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2020 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Jul 23, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q19/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a cosmetic composition for inhibiting or improving seborrhea and a pharmaceutical composition for preventing, improving or treating seborrhea, each composition comprising a specific peptide as an active ingredient. The peptide remarkably decreases the interaction between p53 and MDM2 and thus remarkably increases the interaction between p53 and RNA Polymerase II (POLII), thereby being able to induce expressions of the cytokines that cause apoptosis of sebocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.