Method for reducing an amount of subvisible particles in a pharmaceutical composition
US12370311B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2023 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Mar 16, 2043 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/0238
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention relates to a method for reducing an amount of sub visible particles in a pharmaceutical composition contained in a medical injection device comprising a container (1) including a barrel (10) lubricated with a lubricant coating (2) in contact with the pharmaceutical composition, and a stopper (14) in sliding engagement within the barrel (10), the container comprising a region (130, 121, 123) extending distally from the distal end (100) of the barrel which is not accessible to the stopper. During formation of said lubricant coating (2) on the inner wall of the barrel, the method comprises limiting lubricant from being deposited into said region (130, 121, 123) extending distally from the distal end (100) of the barrel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.