Patent · US Active

Aryl hydrocarbon receptor agonists and uses thereof

US12371408B2 · kind B2 · utility

0Cited by
0References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 5, 2024
Grant dateJul 29, 2025
Priority date
Expiry dateFeb 5, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/6512
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to pharmaceutical compounds of Formula (I): as further described herein, and pharmaceutical compositions containing such compounds, as well as methods of using these compounds to modulate the activity of aryl hydrocarbon receptor (AhR) and to treat conditions comprising inflammation inside the intestinal tract and certain disorders of the central nervous system affected by the gut-brain axis, including IBD, ulcerative colitis, Crohn's disease, Huntington's disease, and multiple sclerosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.