Aryl hydrocarbon receptor agonists and uses thereof
US12371408B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2024 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Feb 5, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6512
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pharmaceutical compounds of Formula (I): as further described herein, and pharmaceutical compositions containing such compounds, as well as methods of using these compounds to modulate the activity of aryl hydrocarbon receptor (AhR) and to treat conditions comprising inflammation inside the intestinal tract and certain disorders of the central nervous system affected by the gut-brain axis, including IBD, ulcerative colitis, Crohn's disease, Huntington's disease, and multiple sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.