Pyridazine derivatives as SMARCA2/4 degraders
US12371426B2 · kind B2 · utility
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15Claims
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Inventors
Key dates
| Filing date | Apr 26, 2019 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Dec 30, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides pyridazine derivatives of formula (I), which are therapeutically useful as SMARCA2/4 degraders. These compounds are useful in the treatment and/or prevention of diseases or disorders dependent upon SMARCA2/4 in a mammal. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the pyridazine derivatives of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.