Methods for obtaining antibodies that bind transmembrane proteins and cells that produce the same
US12371487B2 · kind B2 · utility
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25References
39Claims
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Key dates
| Filing date | Dec 22, 2021 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Jun 7, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/33
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are methods for obtaining cells that express antibodies that bind transmembrane proteins, methods for generating antibodies from such cells, antibodies to transmembrane proteins and fragments thereof, and nucleic acids encoding the antibodies. More particularly, the disclosure relates to methods for obtaining antibody-producing cells that express an antibody that binds to a transmembrane protein based on the use of lipid bilayer-membrane scaffold protein complexes to present transmembrane protein antigens to cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.