Patent · US Active

Antibodies specific to MUC18

US12371509B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

Multitude Inc. · CN

Inventors

Bing Hou · Shanghai, CN
Peng CHEN · Shanghai, CN
Junli Liu · Bothell, US
Shu-Hui Liu · Redwood City, US
Xun Meng · Shanghai, CN

Key dates

Filing date	Jun 17, 2021
Grant date	Jul 29, 2025
Priority date	—
Expiry date	Mar 28, 2044

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/33
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antibodies specific to MUC18 (a.k.a. MCAM or CD146) and uses thereof for therapeutic and diagnostic purposes are provided. Also provided herein are chimeric antigen receptors (CARs) comprising an extracellular antigen-binding fragment that binds MUC18 and immune cells expressing such.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.