Methods for chromatography resin slurry determination
US12372502B2 · kind B2 · utility
0Cited by
7References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 2018 |
| Grant date | Jul 29, 2025 |
| Priority date | — |
| Expiry date | Oct 15, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/565
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for determining a slurry concentration for a slurry of a chromatography resin during a column packing. The present invention provides a more accurate and consistent method for determining a slurry concentration for packing a chromatography column. The method of the present invention utilizes an automated pump to provide a controlled flow rate to consolidate a resin sample. Based on the consolidated resin, a slurry concentration can be determined. The determined slurry concentration can be utilized to pack the resin in a chromatography column with highly accurate bed heights.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.