Hyaluronic acid nanoparticles comprising NADPH oxidases inhibitors and uses in treating cancer
US12377117B2 · kind B2 · utility
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Key dates
| Filing date | Apr 1, 2020 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Jun 26, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This disclosure relates to hyaluronic acid nanoparticles containing an anticancer agent such as a NADPH oxidase (NOX) inhibitor for targeted delivery to cancerous cells or tumors. In certain embodiments, the nanoparticles are made up of hyaluronic acid conjugated to hydrophobic moieties. In certain embodiments, the hydrophobic moieties are steroid based compounds, such as 5beta-cholanic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.