Systems, apparatus and kits for enzymatic polynucleotide synthesis
US12377397B2 · kind B2 · utility
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23References
12Claims
0Family size
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Key dates
| Filing date | Jun 14, 2021 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Oct 8, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00722
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention is directed to systems, apparatus and kits for automated synthesis of a plurality of polynucleotides in an array of reaction chambers using a template-free polymerase. In some embodiments, adaptive elements and processes are provided to monitor and control disruption of the synthesis process and fluid movement by enzyme aggregation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.