Blood brain barrier-on-a-chip
US12377413B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 30, 2021 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Jan 23, 2043 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a blood-brain barrier vascular network implemented in a microfluidic chip. The blood-brain bather vascular network structure (BBB on a chip) (in vitro blood-brain bather (BBB)-on-a chip) formed in a microfluidic chip manufactured by a present manufacturing method of the in vitro blood-brain barrier (BBB)-on-a chip may reconstruct the blood-brain barrier in a real human body more similarly due to a specific cell configuration, compared to the conventional in vitro blood-brain barrier (BBB)-on-a chip, and thus may be used as a more accurate in vitro blood-brain barrier, and may be used for the development of various cellular therapeutic agents or drugs that work in the treatment of various brain diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.