Inhibitors of meprin α and β

US12378186B2 · kind B2 · utility

Assignee

• VIVORYON THERAPEUTICS N.V. · DE

Inventors

• Michael Wermann · Halle (Saale), DE
• Mirko Buchholz · Halle (Saale), DE
• Hans-Ulrich Demuth · Halle (Saale), DE
• Daniel Ramsbeck · Halle (Saale), DE
• Dagmar Schlenzig · Bodenwerder, DE
• Stephan Schilling · Halle (Saale), DE

Key dates

• Filing date: Mar 8, 2021
• Grant date: Aug 5, 2025
• Expiry date: Mar 8, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D319/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel hydroxamic acid derivatives as inhibitors of meprin β and/or α, pharmaceutical compositions comprising such compounds, methods for treatment or prophylaxis of diseases or conditions, especially such that are related to meprin β and/or α, and compounds and pharmaceutical compositions for use in such methods.