Patent · US Active

Tetrahydrobenzoazepinones and related analogs for inhibiting YAP/TAZ-TEAD

US12378202B2 · kind B2 · utility

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19Claims
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Key dates

Filing dateDec 23, 2022
Grant dateAug 5, 2025
Priority date
Expiry dateDec 23, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.