Patent · US Active

Heterocyclic THR-β receptor agonist compound and preparation method and use therefor

US12378268B2 · kind B2 · utility

0Cited by

0References

24Claims

0Family size

Assignee

Hepagene Therapeutics (HK) Limited · CN

Inventors

Shanghai Yu · Shanghai, CN
Ben Li · Po Tong Ha, CN

Key dates

Filing date	Oct 19, 2020
Grant date	Aug 5, 2025
Priority date	—
Expiry date	Jul 7, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/657181
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A chemical compound shown in formula (I) below and an isomer thereof or a pharmaceutically acceptable salt thereof. The compound improves THR-β agonistic activity while also improving selectivity for THR-α, thereby improving pharmaceutical quality.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.