Patent · US Active

Convergent liquid phase syntheses of oligonucleotides

US12378276B2 · kind B2 · utility

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2References
17Claims
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Key dates

Filing dateMay 8, 2020
Grant dateAug 5, 2025
Priority date
Expiry dateSep 21, 2042

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure describes a convergent liquid phase process for manufacturing oligonucleotides by coupling two or more oligonucleotide fragments, each of which have two or more nucleotides. Also provided by the present disclosure are reaction steps involved the convergent liquid phase process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.