Anti-CD137 molecules and use thereof
US12378319B2 · kind B2 · utility
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50References
13Claims
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Key dates
| Filing date | Dec 28, 2021 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Jun 16, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides antibodies that bind to human CD137 or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, and for the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.