Platelets as delivery agents
US12378523B2 · kind B2 · utility
0Cited by
66References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 28, 2023 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Jul 28, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are RNA agent-loaded platelets, methods of preparing RNA agent-loaded platelets, and methods of using RNA agent-loaded platelets. In some embodiments, methods of loading RNA agents into platelets include treating platelets with a RNA agent, a cationic transfection reagent, and a loading buffer that can include a salt, a base, a loading agent, and optionally at least one organic solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.