Patent · US Active

Use of RNA for reprogramming somatic cells

US12378531B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

BIONTECH SE · DE

Inventors

Ugur Sahin · Mainz, DE
Marco Poleganov · Frankfurt, DE
Tim Beissert · Groß-Gerau, DE

Key dates

Filing date	Apr 27, 2021
Grant date	Aug 5, 2025
Priority date	—
Expiry date	Jan 28, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Methods for effecting the de-differentiation of somatic cells to cells having stem cell characteristics, in particular pluripotency, include the steps of introducing RNA encoding factors inducing the de-differentiation of somatic cells into the somatic cells and culturing the somatic cells allowing the cells to de-differentiate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.