Fusion proteins comprising acid alpha-glucosidase enzymes and methods thereof
US12378540B1 · kind B1 · utility
0Cited by
10References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2025 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Mar 17, 2045 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are proteins, which are capable of being transported across the blood-brain barrier (BBB) and comprise an acid alpha-glucosidase (GAA) enzyme-Fc fusion polypeptide. Certain embodiments also provide methods of using such proteins to treat Pompe disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.