Transgenic mouse models supporting innate immune function
US12378574B2 · kind B2 · utility
0Cited by
0References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 13, 2020 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Oct 7, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2517/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein, in some aspects, is a NOD.Cg-Prkdcscid Il2rgtm1wjl/SzJ (NOD scid gamma or NSG™) mouse comprising a nucleic acid encoding human FLT3L and an inactivated mouse Flt3 allele, methods of producing the mouse, and methods of using the mouse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.