Patent · US Active

Co-production pathway for 3-HPA and acetyl-CoA derivatives from malonate semialdehyde

US12378580B2 · kind B2 · utility

0Cited by
7References
22Claims
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Key dates

Filing dateJul 1, 2022
Grant dateAug 5, 2025
Priority date
Expiry dateMar 23, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y203/01009
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present disclosure provides methods for utilizing genetically modified microbes to co-produce 3-hydroxypropionic acid (3-HP) and acetyl-CoA, and derivatives thereof from malonate semialdehyde as a common single intermediate. The disclosure further provides modified microbe that co-produce the 3-HP and acetyl-CoA derivatives from malonate semialdehyde.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.