Co-production pathway for 3-HPA and acetyl-CoA derivatives from malonate semialdehyde
US12378580B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Jul 1, 2022 |
| Grant date | Aug 5, 2025 |
| Priority date | — |
| Expiry date | Mar 23, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y203/01009
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides methods for utilizing genetically modified microbes to co-produce 3-hydroxypropionic acid (3-HP) and acetyl-CoA, and derivatives thereof from malonate semialdehyde as a common single intermediate. The disclosure further provides modified microbe that co-produce the 3-HP and acetyl-CoA derivatives from malonate semialdehyde.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.