Neisseria meningitidis compositions and methods thereof

US12383611B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Annaliesa Sybil Anderson · Upper Saddle River, US
• John Lance Perez · Doylestown, US
• Kathrin Ute Jansen · Doylestown, US
• Paul Liberator · Holmdel, US
• Cuiwen Tan · Ridgewood, US
• Thomas Richard Jones · New City, US
• Johannes Frederik Beeslaar · Farnham, GB
• Judith Absalon · New York, US
• Jason Douglas Maguire · Chesapeake, US
• Shannon Lea Harris · Nanuet, US

Key dates

• Filing date: Sep 24, 2020
• Grant date: Aug 12, 2025
• Expiry date: Sep 24, 2040

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

In one aspect, the disclosure relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide, and methods of use thereof. The disclosure further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.