Modulators of mas-related g-protein receptor X2 and related products and methods
US12384748B2 · kind B2 · utility
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Key dates
| Filing date | Mar 25, 2024 |
| Grant date | Aug 12, 2025 |
| Priority date | — |
| Expiry date | Mar 25, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for modulating MRGPR X2 generally, or for treating a MRGPR X2 dependent condition more specifically, by contacting the MRGPR X2 or administering to a subject in need thereof, respectively, an effective amount of a compound having structure (I): or a pharmaceutically acceptable salt, isomer, hydrate, solvate or isotope thereof, wherein W, Z, R1, R2, R3, R4, R5, R6 and Rx are as defined herein. Pharmaceutical compositions containing such compounds, as well as the compounds themselves, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.