Methods of synthesizing substituted pyridinone-pyridinyl compounds
US12384757B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Aug 10, 2023 |
| Grant date | Aug 12, 2025 |
| Priority date | — |
| Expiry date | Aug 14, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermediates. Also disclosed is the multi-kilogram preparation of several novel intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.