Patent · US Active

Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia

US12384797B2 · kind B2 · utility

0Cited by

6References

17Claims

0Family size

Assignee

PTC THERAPEUTICS, INC. · US

Inventors

Nanjing Zhang · Princeton, US
Michael A. Arnold · Flemington, US
Amal Dakka · Whitehouse Station, US
Gary Mitchell Karp · Princeton, US
Tom Tuan Luong · Cupertino, US
Jana Narasimhan · Scotch Plains, US
Nikolai Naryshkin · East Brunswick Township, US
Jiashi Wang · Monmouth Junction, US
Xiaoyan Zhang · Lexington, US

Key dates

Filing date	Feb 10, 2020
Grant date	Aug 12, 2025
Priority date	—
Expiry date	May 31, 2042

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present description relates' to compounds of formula (I) useful for improving pre-mRNA splicing in a cell. In particular, another aspect of the present description relates to substituted thieno[3,2-b]pyridine compounds, forms, and pharmaceutical compositions thereof and methods of use for treating or ameliorating familial dysautonomia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.