Patent · US Active

Activatable masked anti-CTLA4 binding proteins

US12384845B2 · kind B2 · utility

0Cited by

19References

14Claims

0Family size

Assignees

Xilio Development, Inc. · US
City of Hope · US

Inventors

John C. Williams · Duarte, US
Margaret Karow · Newbury Park, US

Key dates

Filing date	Dec 26, 2019
Grant date	Aug 12, 2025
Priority date	—
Expiry date	Dec 9, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/50
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides activatable masked anti-CTLA4 binding proteins (e.g., antibodies, bispecific antibodies, and chimeric receptors) and their use in treating and preventing cancer, as well as compositions and kits comprising the activatable masked anti-CTLA4 binding proteins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.