CRISPR-Cas system for clostridium genome engineering and recombinant strains produced thereof
US12385023B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Sep 8, 2021 |
| Grant date | Aug 12, 2025 |
| Priority date | — |
| Expiry date | Jun 13, 2044 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A system for modifying the genome of Clostridium strains is provided based on a modified endogenous CRISPR array. The application also describes Clostridium strains modified for enhanced butanol production wherein the modified strains are produced using the novel CRISPR-Cas system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.