Small molecules that bind and/or modulate differentforms of tau oligomers

US12391657B2 · kind B2 · utility

Assignees

• The Board of Regents of the University of Texas System · US
• UNIVERSITY OF PALERMO · IT

Inventors

• Rakez Kayed · Galveston, US
• Filippa Lo Cascio · Villaggio Santa Barbara, IT
• Antonio Palumbo Piccionello · Villaggio Santa Barbara, IT
• Andrea Pace · Villaggio Santa Barbara, IT

Key dates

• Filing date: Apr 23, 2020
• Grant date: Aug 19, 2025
• Expiry date: Oct 12, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C255/42
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to novel small molecules of Formulas I, II, III, Ilia, Illb, and IV and pharmaceutically acceptable salts thereof, as well as the preparation and the use thereof.