Synthesis of key intermediate of KRAS G12C inhibitor compound
US12391689B2 · kind B2 · utility
0Cited by
54References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2022 |
| Grant date | Aug 19, 2025 |
| Priority date | — |
| Expiry date | Oct 22, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C309/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.