Synthesis of key intermediate of KRAS G12C inhibitor compound
US12391691B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Dec 19, 2024 |
| Grant date | Aug 19, 2025 |
| Priority date | — |
| Expiry date | Dec 19, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C309/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.