Solid polymorphs of a FLNA-binding compound and its hydrochloride salts
US12391693B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Nov 21, 2024 |
| Grant date | Aug 19, 2025 |
| Priority date | — |
| Expiry date | Nov 21, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The preparation and properties of crystalline polymorphs and solvates of 1-benzyl-8-methyl-1,4,8-triazaspiro-[4.5]-decan-2-one free base and of the mono- and dihydrochloride salts and solvates thereof are disclosed, as is an amorphous polymorph of the dihydrochloride. A pharmaceutical composition containing one or more polymorphs and a method of using that composition are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.