Patent · US Active

Antigen binding molecule formats

US12391753B2 · kind B2 · utility

0Cited by

3References

22Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Tong Zhang · Beijing, CN
Samuel Davis · New York, US
Chia-Yang Lin · Palo Alto, US
Eric Smith · New York, US
Erica Pyles · New City, US
Michael Rosconi · New City, US
Nina Liu · Chappaqua, US
Supriya Patel · Mamaroneck, US
Andrew J. Murphy · Croton-on-Hudson, US

Key dates

Filing date	Dec 11, 2024
Grant date	Aug 19, 2025
Priority date	—
Expiry date	Dec 11, 2044

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.