Substituted imidazo[1,2-α]pyrazines as luciferase substrates
US12391973B2 · kind B2 · utility
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Key dates
| Filing date | Aug 29, 2023 |
| Grant date | Aug 19, 2025 |
| Priority date | — |
| Expiry date | Oct 20, 2043 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90241
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods from making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.