Optical discrimination apparatus and methods adapted to monitor reactions
US12391982B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2021 |
| Grant date | Aug 19, 2025 |
| Priority date | — |
| Expiry date | Sep 5, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/0635
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An optical discrimination apparatus adapted for use in PCR testing and the like. The apparatus includes a multi-color light emitter to emit excitation light, a sample holder configured to hold dye-marked nucleic acid fragments in a PCR solution at a position configured to receive the excitation light along a first direction, light emission collection optics configured to collect scattered excitation light and light emission (fluorescent emission) from the sample holder along a second direction that is approximately orthogonal to the first direction, a spectrally-dispersive element configured to spectrally disperse scattered light and emission light, and a spectral detector configured to receive the separated emission light and excitation light on different photosites of the spectral detector. Systems and methods are provided, as are other aspects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.