Patent · US Active

Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries

US12397008B2 · kind B2 · utility

0Cited by

2References

12Claims

0Family size

Assignee

Lead Billion Limited · CN

Inventors

Ming Li · Hong Kong, CN
Lei Cheng · Kunshan, CN
Hong Liu · Shanghai, CN

Key dates

Filing date	Jul 13, 2021
Grant date	Aug 26, 2025
Priority date	—
Expiry date	Aug 12, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J63/008
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages cause by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.