Polyphenol compositions and uses thereof
US12397030B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 23, 2020 |
| Grant date | Aug 26, 2025 |
| Priority date | — |
| Expiry date | Apr 9, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This disclosure provides a composition and a method for enhancing urolithin B production. As a result of this, due to known impact of urolithin B, this can enhance reverse cholesterol transport and HDL function and management of plasma lipid profile through enhanced production of urolithin B from pomegranate polyphenols by administering a composition comprising a synergistic mixture of pomegranate polyphenols, lycopene and quercetin. The improved HDL function and lipid profile of such composition may be attributed to the enhanced urolithin B production made possible by the combination. Increasing the levels of urolithin B through modulation of the intestinal microbiome metabolism of pomegranate polyphenols is a potential therapeutic target for managing these diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.