Methods for converting CBD, CBDA and analogs thereof into Δ8-THC, Δ8-THCA and analogs thereof
US12398113B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Dec 16, 2021 |
| Grant date | Aug 26, 2025 |
| Priority date | — |
| Expiry date | Jun 26, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/78
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are methods for converting cannabidiol, cannabidiolic acid and analogs thereof into Δ8-tetrahydrocannabinol, Δ8-tetrahydrocannabinolic acid and analogs thereof. In particular, there is provided a method for converting a compound of Formula (I) as defined herein into a compound of Formula (II) as defined herein, the method comprising heating the compound of Formula (I) and a Lewis acidic heterogeneous reagent in an aprotic-solvent system to provide a compound of Formula (II), wherein the Lewis-acidic heterogeneous reagent is acidic alumina.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.