Binding agents binding to EpCAM and CD137

US12398214B2 · kind B2 · utility

Assignees

• GENMAB A/S · DK
• BIONTECH SE · DE

Inventors

• Andreea Ioan · Utrecht, NL
• Esther BREIJ · Utrecht, NL
• Lars Guelen · Utrecht, NL
• David Satijn · Utrecht, NL
• Ugur Sahin · Mainz, DE
• Alexander Muik · Seeheim-Jugenheim, DE
• Kristina Nürmberger · Mainz, DE
• Sina Fellermeier-Kopf · Mainz, DE
• Bart-Jan DE KREUK · Utrecht, NL
• Richard HIBBERT · Utrecht, NL
• Janine Schuurman · Utrecht, NL
• Aran Frank Labrijn · Amsterdam, NL

Key dates

• Filing date: Mar 15, 2023
• Grant date: Aug 26, 2025
• Expiry date: Mar 15, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K16/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a binding agent that binds to EpCAM and to CD137 which is useful to treat or prevent a tumor or cancer, or to prevent progression of a tumor or cancer.