Methods of classifying diffuse large B-cell lymphoma
US12400737B2 · kind B2 · utility
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Key dates
| Filing date | Oct 9, 2019 |
| Grant date | Aug 26, 2025 |
| Priority date | — |
| Expiry date | Jun 5, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H10/40
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of predicting if a subject has an Activated B Cell-like (ABC) subtype or a non-ABC subtype of Diffuse Large B-Cell Lymphoma (DLBCL), comprising (a) obtaining a sample from the subject; (b) measuring the expression levels of CD10, MUM1, FOXP1, and optionally Bcl-6; (c) determining a composite score based on the expression levels of CD10, MUM1, and FOXP1, and optionally Bcl-6; and (d) predicting if the subject has an ABC subtype or a non-ABC subtype of DLBCL based on the composite score.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.