HECT E3 ligase inhibitors and uses thereof
US12403144B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Jun 3, 2020 |
| Grant date | Sep 2, 2025 |
| Priority date | — |
| Expiry date | Sep 1, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to tricyclic derivatives of formula (I), which are useful as inhibitors of HECT-domain-containing E3 ligases, in particular NEDD4. The present invention also refers to pharmaceutical compositions comprising compounds of formula (I), to their medical use and to their process of preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.