Patent · US Active

Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof

US12403181B2 · kind B2 · utility

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17Claims
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Key dates

Filing dateAug 13, 2019
Grant dateSep 2, 2025
Priority date
Expiry dateJul 23, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K16/245
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a combination of i) interleukin-2 (IL-2) and ii) an interleukin 1 (IL-1) inhibitor, for use in treating an auto-immune and/or inflammatory disorder in a subject. It is also provided a pharmaceutical composition comprising interleukin-2 (IL-2) and an interleukin-1 (IL-1) inhibitor. The invention further provides a conjugate comprising IL-2 conjugated to an IL-1 inhibitor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.