Preparation method for trans-cyclobutane-o-dicarboxylic acid ester and derivative thereof
US12404229B2 · kind B2 · utility
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Key dates
| Filing date | Oct 25, 2019 |
| Grant date | Sep 2, 2025 |
| Priority date | — |
| Expiry date | Sep 24, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A preparation method for a trans-cyclobutane-o-dicarboxylic acid ester and a derivative thereof includes the following steps: in an organic solvent, catalyzing a substrate with a structure as shown in a structural formula I by using organic alkali at 50-90° C. so as to generate isomerization, acquiring the trans-cyclobutane-o-dicarboxylic acid ester or the derivative thereof, herein the structural formula I is as follows: Each R1, R2, R3 and R4 is independently one of hydrogen or an alkyl of C1-C5, and each of R5 and R6 is independently one of alkyl of C1-C10 and benzyl.
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