Patent · US Active

Compounds and compositions for intracellular delivery of therapeutic agents

US12404232B2 · kind B2 · utility

0Cited by
83References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 30, 2021
Grant dateSep 2, 2025
Priority date
Expiry dateJun 17, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/18
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.