Patent · US Active

Methods and compositions for use of recombinant bacterial effector proteins as anti-inflammatory agents

US12404307B2 · kind B2 · utility

0Cited by

2References

12Claims

0Family size

Assignees

The Wistar Institute of Anatomy and Biology · US
Innate Biologics LLC · US

Inventors

Frank Rauscher · Wayne, US
Peter Mondics · Newtown Square, US

Key dates

Filing date	Mar 3, 2022
Grant date	Sep 2, 2025
Priority date	—
Expiry date	Mar 3, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/70
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are methods and compositions comprising a set of paired peptides comprising a first bacterial effector polypeptide or fragment thereof linked to a second bacterial effector polypeptide or fragment thereof. The paired peptides can be linked to a protein transduction domain. The compositions can be formulated as pharmaceuticals. The compositions are useful for the treatment of inflammatory disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.