Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers
US12404349B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Oct 3, 2023 |
| Grant date | Sep 2, 2025 |
| Priority date | — |
| Expiry date | Oct 3, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0087
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of attaching a mannose-binding C-type lectin receptor targeting moiety to a polymeric carbohydrate backbone using an amide linkage. The amide linkage may be found between a leash, such as an amine terminated leash, and the mannose-binding C-type lectin receptor targeting moieties. The compounds and compositions disclosed utilizing the amide linkage provide for highly stable compounds with a significant reduction in loss of mannose-binding C-type lectin receptor targeting moieties from the polymeric carbohydrate backbone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.