Method for making a physical map of binding events that are on or on cells
US12404545B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | May 19, 2025 |
| Grant date | Sep 2, 2025 |
| Priority date | — |
| Expiry date | May 19, 2045 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein is a method comprising producing rolling circle amplification (RCA) products that are immobilized in or on cells, wherein each RCA product has an RCA product identifier sequence that distinguishes the RCA product from other RCA products that are immobilized in or on the cells; while the RCA products are immobilized in or on cells, producing nucleic acid products that contain RCA product identifier sequences or complements thereof from adjacent RCA products; for each of a plurality of the nucleic acid products, identifying which RCA product identifier sequences or complements thereof are in the nucleic acid product; and making a physical map of at least some of the RCA products using the identified RCA product identifier sequences or complements thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.