Particles for use in hyperpolarization
US12409239B2 · kind B2 · utility
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5References
14Claims
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Inventor
Key dates
| Filing date | Jun 23, 2022 |
| Grant date | Sep 9, 2025 |
| Priority date | — |
| Expiry date | Jun 23, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/1818
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are particles comprising a crystalline matrix and a dopant, wherein one of the atoms of the matrix is 19F and 31P, or 13C, 15N, 29Si, 16O, 17O, 23Na, 39K, 25Mg, 40Ca, 43Ca or deuterium; and the dopant is a compound involved in a biological process in a mammalian organism; and wherein the dopant is present in an amount of between 0.01% and 20% of the plurality of particles, and wherein when the matrix comprises an atom selected from the group of 13C, 15N, 29Si, 16Q, 17O, 23Na, 39K, 25Mg, 40Ca, 43Ca and deuterium, and the dopant is isotopically enriched.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.