Chiral synthesis of a tertiary alcohol
US12410204B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Nov 12, 2020 |
| Grant date | Sep 9, 2025 |
| Priority date | — |
| Expiry date | Sep 29, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are methods for preparing tertiary alcohols from an optionally substituted phenyl ketone or an optionally substituted pyridinyl ketone that includes the use of a chiral ligand and boron trifluoride diethyl etherate. Tertiary alcohols can be used to prepare synthetic versions of natural products and/or pharmaceuticals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.