Fusokines involving cytokines with strongly reduced receptor binding affinities
US12410222B2 · kind B2 · utility
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3References
2Claims
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Key dates
| Filing date | Apr 29, 2022 |
| Grant date | Sep 9, 2025 |
| Priority date | — |
| Expiry date | Mar 18, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.