Patent · US Active

Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same

US12410261B2 · kind B2 · utility

0Cited by
21References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 27, 2024
Grant dateSep 9, 2025
Priority date
Expiry dateMar 27, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2510/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to a novel anti-HER2 antibody or an antigen-binding fragment thereof used in the prevention or treatment of cancer, a chimeric antigen receptor including the same, and uses thereof. The antibody of the present disclosure is an antibody that specifically binds to HER2 which is highly expressed in cancer cells (particularly, breast cancer or gastric cancer cells), and binds to an epitope that is different from an epitope to which trastuzumab binds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.