Phosphorylated polypeptide antigen vaccine, preparation method therefor and application thereof
US12414987B2 · kind B2 · utility
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34Claims
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Key dates
| Filing date | Mar 26, 2019 |
| Grant date | Sep 16, 2025 |
| Priority date | — |
| Expiry date | Dec 10, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a phosphorylated polypeptide antigen vaccine, comprising at least two polypeptide fragments or conservatively modified variants thereof from human full-length Tau protein, wherein the polypeptide fragments or conservatively modified variants thereof contain phosphorylation sites. The present invention also discloses a complex vaccine formed by coupling a phosphorylated polypeptide antigen vaccine with a carrier. The polypeptide antigen vaccine and the complex vaccine can be used for preventing and/or treating tauopathy comprising Alzheimer's disease (AD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.